感染症與疫苗研究所
連絡電話：(+886) 037-246166 ext.35532
傳真電話：(+886) 037-586457
電子郵箱：frchen@nhri.org.tw
學歷
| 1993 – 1999 | Ph.D., Aquaculture, National Taiwan Ocean University,, Taiwan |
| 1991 – 1993 | M.S., Marine Biology, National Taiwan Ocean University, Taiwan |
| 1987 – 1991 | B.S., Aquaculture, National Taiwan Ocean University, Taiwan |
經歷
| 2006 – present | Assistant Investigator, Division of Infectious Diseases, National Health Research Institutes, Taiwan |
| 2004 – 2006 | Research Associate, Division of Clinical Research, National Health Research Institutes, Taiwan |
| 2003 – 2004 | Research Associate, Institute of Infection, Immunity and Inflammation, University of Nottingham, UK |
| 1999 – 2003 | Postdoctoral Fellow, Division of Clinical Research, National Health Research Institutes, Taiwan |
Research Interests
Dr. Chen’s main research interests include virulence regulation and drug resistance in Staphylococcus aureus. Current focus is on the regulation of virulence genes by a quorum sensing system. Quorum sensing is one particular form of cell-to-cell communication, in which genes are expressed in response to changes in population density. The opportunity is there for the exploitation of quorum sensing as a novel target for anti-infective therapy. It will be interesting to see this opportunity translated into clinical reality.
Research Activities & Accomplishment
Dr. Chen had studied the molecular mechanisms of fluoroquinolone reduced susceptibility in Escherichia coli and Klebsiella pneumoniae and has published some research articles about this issue.
NHRI Repository: http://ir.nhri.org.tw/handle/3990099045/120