研究人員>周彥宏 (Yenhung Joe Chow)

周彥宏照片

感染症與疫苗研究所

連絡電話:(+886) 037-246166 ext. 37738

傳真電話:(+886) 037-583009

電子郵箱:choeyenh@nhri.edu.tw

學歷

1992 – 1997 PhD, Institutes of Life Science, National Defense Medical Center, Taipei, Taiwan
1990 – 1992 MS, Dept. of Pharmacology, National ChenKung University, Tainan, Taiwan
1986 – 1990 BSc, Dept. of Pharmacy, Kaoshung Medical University, Kaoshung, Taiwan

經歷

2006/05 – 2010/02 Adjunct Assistant Professor, Graduate Institute of Biopharmaceutics, National Chiayi University, Chiayi, Taiwan
2006/02 – present Assistant Principle Investigator, Vaccine R&D Center, National Health Research Institutes, Zhunan, Taiwan
2005/07 – 2006/05 Assistant Professor, Dept. of Infectious Disease, University of Georgia, Athens, GA, USA
2002 – 2005/07 Research Associate, Dept. of Infectious Disease, University of Georgia, Athens, GA, USA
2001 – 2002 Post-doctoral fellow, Laboratory of Experimental and Computational Biology, National Cancer Institute, National Institute of Health, USA
2000 Post-doctoral fellow, Dept. of Oral Biology and Medicine, School of Dentistry, University of California, USA

Honors & Awards

2015 – 2015 The 12th National Innovation Award
2003 – 2003 Presentation and travel award of 2003 Human retrovirus Conference. Keystone, Colorado
2001 – 2001 Oral presentation and travel award of 2001 AIDS Vaccine Conference, Philadelphia
2000 – 2007 Member of American Association of Cancer Research (AACR) (2000-present)
2000 – 2000 Presentation and travel award of 2000 International Human Retrovirus Annual Conference, Baltimore
1999 – 2004 Member of American Association of Cancer Research (AACR) (2000-present)
1996 – 1996 Award of the Best Thesis of the year, Molecular Cell Biology Association

Expertise

1. Molecular Virology 2. Vaccine Development 3. Tumor Biology 4. Signal Transduction

Research Interests

  1. Development of a lung adenocarcinoma mice model to study the mechanisms of tumorgenesis (2007-2010). These studies are helping us to develop a model for cancer study and prevention.
  2. Development of recombinant mucosal vaccines against the respiratory syncytial virus (RSV) (2008-present); a, adenovirus and rubella delivery vectors expressing RSV fusion protein as vaccine and tested their immunogenicity in mice; b, identification of HLA-restricted CTL epitope of RSV fusion protein. c, Study the mechanism of RSV-inudced lung pathology. These achievements will provide us useful mucosal delivery system to develop vaccine for RSV and other respiratory infectious agents. d, Establishment and production of human-used Ad-RSV vaccine in cGMP manufactory in Vaccine R&D Center, NHRI.
  3. Creation of an EV71 infectious mice model for EV71 vaccine development (2009-present): a, study of the mechanisms of hand-foot-and mouth disease (HFMD) occurred in SCARB2-expressing mouse infected with EV71; b, study of the mechanism of EV71 entry. These results will accelerate the development of EV71 vaccine.
  4. Development of Ad-VLP as a multivalent vaccine against HFMD.

Research Activities & Accomplishment

Dr. Chow has 42 peer-reviewed journals and 8 granted patents and 2 filing patents Dr. has awarded the 12th National Innoviation Award, 2015 Dr. has tech-transferred Ad-RSV vaccine to BioChina, INc.


NHRI Repository: http://ir.nhri.org.tw/handle/3990099045/832

NHRI Repository (patent): http://ir.nhri.org.tw/handle/3990099045/833


 

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